DETAILS, FICTION AND LDN-27219 PHARMACOLOGICAL PROPERTIES

A person specially appealing compound is LDN-27219. Even though most tTG inhibitors are created to bind into the protein crosslinking Energetic website, LDN-27219 rather binds to the nucleotide binding pocket with the enzyme even though it is actually in its closed-condition conformation, and stabilizes that conformation to stop crosslinking activi